Details
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Type: Bug
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Status: Open
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Priority: Major
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Resolution: Unresolved
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Affects Version/s: 2.10.1
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Fix Version/s: None
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Component/s: analysis
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Labels:None
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Mantis ID:15021
Description
Identical sequences get greater pairwise distances than pairs of sequences with certain single point mutations - is the distance matrix calculation correct for blosum62 ? (ie - the raw diagonal elements of the matrix are being used - which are the log-odd abundance for the residue rather than the likelihood of mutation).
Attachments
Issue Links
- related with
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JAL-374 PID pairwise distance miscalculated as zero for unaligned sequences in UPGMA tree view
- In Progress