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  1. Jalview
  2. JAL-210

Suspect Blosum62 based tree calculation

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    Details

    • Type: Bug
    • Status: Open
    • Priority: Major
    • Resolution: Unresolved
    • Affects Version/s: 2.10.1
    • Fix Version/s: None
    • Component/s: analysis
    • Labels:
      None
    • Mantis ID:
      15021

      Description

      Identical sequences get greater pairwise distances than pairs of sequences with certain single point mutations - is the distance matrix calculation correct for blosum62 ? (ie - the raw diagonal elements of the matrix are being used - which are the log-odd abundance for the residue rather than the likelihood of mutation).

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              Assignee:
              gmungoc Mungo Carstairs
              Reporter:
              jprocter James Procter
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                Dates

                Created:
                Updated: